Based on the data of flood peak levels and flood disaster losses in Lake Poyang region during the period of 1950-2002, this paper established the correlation model between the annual flood peak levels and flood disaster losses, analysed the statistical pattern and regularity of flood disasters and flood disaster losses in Lake Poyang. A scheme of 6-grades was established for floods and areas of flooing in the Poyang region, which revealed that most of the floods occurred once every 2-5 year and are smaller than Grade 3 flood (once every ten year). Lake Poyang had 24 floods during 1950-2002, which accounts 1/3 of total flood disaster losses of this period. Although, Grade 4 floods (once every 5 year) were recorded only 7 times, they account 2/3 of total flood disaster losses. We believe, to low peak flood levels by comprehensive and integrated measures and management, and to increase the capacity of flood prevention for the dyked lakeside farmland are the effective options for mitigation of flood damages and losses.